Torasemide
For an informed discussion with your doctor or pharmacist. This information collection is not a clinically validated interaction checker. Missing data do not establish safety. Do not change or stop prescribed medicines on the basis of this information. The findings apply to the specific conditions studied; laboratory and animal studies cannot be directly extrapolated to humans.
Active substance: Torasemide
Examples of brand names: Torem [DE]
ATC code: C03CA04
Main use (for orientation): Oedema; heart failure
Documented research summary
Within the documented search scope, no sufficiently attributable cannabinoid pair is established for Torasemide. The structured assessment distinguishes documented drug context from the absence of specific interaction evidence. Missing data do not establish safety.
Uncertainties and limitations
Do not present model values as patient data; exposure and electrolyte effects remain unresolved. Do not independently change prescribed medicines on the basis of this research dataset.
Structured assessment
Category: Drug context
Cannabinoid scope: No specifically substantiated pair involving a registered cannabinoid in the material assessed; no claim that all 28 cannabinoids were comprehensively reviewed simultaneously.
Evidence status: Drug properties supported by product information; insufficient evidence for a specific cannabinoid–drug pair effect.
Mechanism / drug context: Mainly CYP2C9, with smaller contributions from CYP2C8/CYP2C18; diuretic effect.
Type of supporting material: Product information and documented individual literature screening; no clinical pair trial approved for use as evidence.
Clinical interpretation: Pharmacokinetic susceptibility is a reason for assessment, not a measured cannabinoid effect.
Context: Computer-based predictions are not experimental or clinical pair validation.
Drug context and gaps in search results are not measured interactions. The source role below describes which statement the source actually supports.
Source role [VD_LABEL_D0228]: Original product information: drug context, not evidence for a cannabinoid–drug pair
Statement supported: Mainly CYP2C9, with smaller contributions from CYP2C8/CYP2C18; diuretic effect.
Source: TORSEMIDE (TORSEMIDE) TABLET [XLCARE PHARMACEUTICALS INC.] – DailyMed SPL [VD_LABEL_D0228]
Source role [VD_MED_41436933]: Documented research / scope-distinction context; no cannabinoid–drug pair evidence approved for use
Statement supported: Computer-based predictions are not experimental or clinical pair validation.
Source: Research on drug-drug interaction prediction using capsule neural network based on self-attention mechanism. [VD_MED_41436933]
Scope of review: Individual research with documented title/abstract screening and targeted review of original sections. This is not exhaustive evidence that interactions are absent.
Unresolved source question: All individual review fields read. Original product information was rechecked only in the relevant pharmacokinetic/interaction excerpts; no complete recertification of all labels or worldwide full-text search. Literature access was based on the previously documented review; only the listed web sources were additionally read in this round. Do not present model values as patient data; exposure and electrolyte effects remain unresolved.
Separately recorded findings
No separately substantiated finding for this drug–cannabinoid pair is recorded within the documented scope of review. This does not prove that no such study exists anywhere or that the combination is safe.
References and access status
[VD_LABEL_D0228] TORSEMIDE (TORSEMIDE) TABLET [XLCARE PHARMACEUTICALS INC.] – DailyMed SPL
Original source / bibliographic reference
Authors: Marketing authorisation holder / label provider according to the linked DailyMed product information
Year: 2024
Source type: Regulatory product information (US SPL)
Source access – 23 October 2026: Source destination was accessible when checked.
Bibliographic attribution or source identity cross-checked.
[VD_MED_41436933] Research on drug-drug interaction prediction using capsule neural network based on self-attention mechanism.
Original source / bibliographic reference
Authors: Chen X, Wang Z, Miao Z, Nie B.
Year: 2025
Source type: research-article; Journal Article
DOI: 10.1186/s12859-025-06308-9
PMID: 41436933
Source access – 23 October 2026: Source destination was accessible when checked.
Bibliographic attribution or source identity cross-checked.
PubMed – bibliographic reference / abstract
Research as of 23 October 2026. Not all original full texts could be reviewed in full. Source accessibility and the strength of scientific evidence must be assessed separately. An accessible link does not establish medical approval; a bibliographic record with an abstract does not replace the original full text.
Drug search and explanation of the evidence · Guide: cannabinoids and medicines · Author and responsibility
Torasemide and cannabinoids: documented findings, evidence, sources and data gaps. Research information for discussion with your doctor or pharmacist.
